Archive: Stochastik Rhein-Main

03.–04.11.2017 Andere Veranstaltungen

Workshop (DFG/ Goethe-Universität Frankfurt)

31.07.–02.08.2019 Andere Veranstaltungen

15. Doktorandentreffen Stochastik

02.–04.09.2019 Andere Veranstaltungen

Miniworkshop Multiple merger coalescents: population models and inference

22.05.2019 Stochastik-Kolloquium Frankfurt

Untersuchung der Überlappungswahrscheinlichkeit in Derrida’s Random Energy Models

28.–30.08.2019 Andere Veranstaltungen

MiniWORKshop: Stochastic processes on evolving networks

08.05.2019 Stochastik-Kolloquium Frankfurt

An introduction to log-correlated fields and multiplicative chaos

15.03.2019 Stochastik-Kolloquium Frankfurt

Wege im vollständigen Graphen mit zufälligen Gewichten

15.03.2019 Stochastik-Kolloquium Frankfurt

Stochastische Analyse von Cuckoo-Hashing

20.02.2019 Stochastik-Kolloquium Frankfurt

Detecting Joint Pauses in Parallel Point Processes

20.02.2019 Stochastik-Kolloquium Frankfurt

Metrische Multidimensionale Skalierung

31.10.2018 Stochastik-Kolloquium Frankfurt

Rekonstruktion zufällig verkürzter Zeichenketten

22.01.2020 Stochastik-Kolloquium Frankfurt

Crossing a fitness valley as a metastable transition in a stochastic population model

07.06.2022 Oberseminar Mainz

Asymptotic behaviour of ancestral lineages in spatial models

19.07.2022 Oberseminar Mainz

Kurzvorträge von Alexander Gieswinkel, Jonathan Klinge, Jakob König (JGU Mainz)

06.06.2024 Stochastik-Kolloquium Frankfurt

B cell phylodynamics and mean-field multi-type birth and death processes

No knowledge of biology will be necessary to understand this talk. Germinal centers (GC) are micro-anatomical structures that transiently form in lymph nodes during an adaptive immune response. In a GC, B cells—the cells that make antibodies—diversify and compete based on the ability of the antibodies they express to recognize a foreign antigen molecule. As GC B cells proliferate, they undergo targeted mutations in the genomic locus encoding the antibody protein that can modify its antigen binding affinity. Via signaling from other GC cell types, the GC can monitor the binding phenotype of the B cell population it contains and provide survival signals to B cells with the highest-affinity antibodies (i.e., birth and death rates depend on type). Motivated by this mechanism, we develop a mean-field model that couples the birth and death rates in a focal multi-type birth and death process (MTBDP) with D types to the empirical distribution of states—i.e., the mean-field over an exchangeable system of N replica MTBDPs. The empirical distribution process of the N replicas converges to a deterministic probability measure-valued flow as N goes to infinity. In the limit, the focal process evolves as a multi-type birth and death process with rates governed by the probability measure-valued flow which is in turn the flow of one-dimensional marginal distributions of the focal process. Individual focal processes become independent in the limit and this holds out the hope of inference being feasible for this model. This is joint work with William S. DeWitt, Ella Hiesmayr, and Sebastian Hummel. Read more

24.–28.03.2025 Sommer-/Winterschule

Spring School 2025

22.10.2019 Oberseminar Mainz

Adrien Schertzer (Goethe Universität Frankfurt)

22.10.19 Adrien Schertzer

25.01.2019 Rhein-Main-Kolloquium

Antti Knowles (Universitär Genf)
Aernout C. D. van Enter (Universität Groningen)

RMK Frankfurt WiSe 2018/2019

02.02.2024 Rhein-Main-Kolloquium

Peter Mörters (Universität Köln)
Alessandra Bianchi (Università degli Studi di Padova)

RMKS Frankfurt/Main 02.02.2024

28.06.2018 Oberseminar Darmstadt

Alessandra Cipriani (University College London)

The scaling limit of the membrane model

Events archive

Events

Workshop (DFG/ Goethe-Universität Frankfurt)

15. Doktorandentreffen Stochastik

Miniworkshop Multiple merger coalescents: population models and inference

Untersuchung der Überlappungswahrscheinlichkeit in Derrida’s Random Energy Models

MiniWORKshop: Stochastic processes on evolving networks

An introduction to log-correlated fields and multiplicative chaos

Wege im vollständigen Graphen mit zufälligen Gewichten

Stochastische Analyse von Cuckoo-Hashing

Detecting Joint Pauses in Parallel Point Processes

Metrische Multidimensionale Skalierung

Rekonstruktion zufällig verkürzter Zeichenketten

Crossing a fitness valley as a metastable transition in a stochastic population model

Asymptotic behaviour of ancestral lineages in spatial models

Kurzvorträge von Alexander Gieswinkel, Jonathan Klinge, Jakob König (JGU Mainz)

B cell phylodynamics and mean-field multi-type birth and death processes

Spring School 2025

22.10.19 Adrien Schertzer

RMK Frankfurt WiSe 2018/2019

RMKS Frankfurt/Main 02.02.2024

The scaling limit of the membrane model

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